Clear cell acanthoma

What is the clear cell? acanthoma?

Clear cell acanthoma is rare benign (not cancerous) epithelial skin tumor. Usually a loner injury popping up on the lower legs, but there have been cases of multiple injuries.

The clear cell acanthoma is also known as the Acanthoma Degos or acanthome à cellules claires.

The clinical features of the injury include:

  • Slightly raised to a dome shape license plate or nodule
  • Color varies from pink to brown, but is generally blood red and bright
  • It can be from 3 to 20 mm in diameter.
  • The crispy wafer-shaped scale It may be stuck around the edges of the injury. A wet or bleeding surface can result if the scale is removed.
Clear cell acanthoma: clinical (top) and dermoscopic (bottom) views


Clear cell acanthoma


Clear cell acanthoma


Acanthoma clear cell dermoscopy


Clear cell acanthoma


Clear cell acanthoma


Acanthoma clear cell dermoscopy

* Images provided by Dr. Jeremy Hay

How is clear cell acanthoma obtained and who is at risk?

It is currently unknown why clear cell acanthoma occurs. Although rare, they occur mainly in middle-aged or older adults. Both men and women can be affected.

How was the diagnosis made?

The diagnosis is rarely made before a skin. biopsy. However, dermoscopy is characteristic, since blood vessels they are lined up in chains (see images above). When examined under a microscope, the clear cell acanthoma shows a characteristic accumulation of clear glycogen-containing cells in the epidermis.

What treatments are available?

They can persist for years and years without changing or causing complications. They are easily removed.

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